Genetoxin 100 – Precision Korean Botulinum Toxin Type A for Safe, Effective Aesthetic & Therapeutic Use
1. Overview & Manufacturer
Genetoxin 100 is a botulinum toxin type A developed by Genetox Co., Ltd., a South Korean pharmaceutical company known for its commitment to producing high-purity, clinical-grade aesthetic injectables.
Genetoxin is formulated for use in both cosmetic wrinkle reduction and therapeutic applications, and is produced in GMP-certified facilities, ensuring international standards of quality, consistency, and safety.2. Composition & Presentation
Each vial contains 100 units of purified Clostridium botulinum toxin type A, in lyophilized (freeze-dried) powder form
Requires reconstitution with 0.9% sterile saline (NaCl) prior to injection
Designed with low protein load, which helps reduce the risk of neutralizing antibody formation over repeated treatments
3. Mechanism of Action
Genetoxin works by blocking the release of acetylcholine at the neuromuscular junction. This results in temporary relaxation of the targeted muscles, which:
Smooths dynamic wrinkles
Softens facial expressions
Reduces muscle hypertrophy (e.g., jawline slimming)
Helps control excessive sweating (hyperhidrosis)
Can relieve spasms and tension in select therapeutic cases
4. Key Advantages
High purity, stable potency – ensures predictable clinical outcomes
Rapid onset – results typically begin to appear within 2 to 4 days
Long-lasting effects – commonly lasts 3 to 6 months, depending on the treatment area and patient response
Smooth, controllable diffusion – ideal for both broad areas (forehead) and delicate zones (crow’s feet)
Affordable and accessible – a high-quality, cost-effective alternative to premium Western brands
5. Clinical Applications
Aesthetic Uses:
Horizontal forehead lines
Glabellar (frown) lines
Crow’s feet (periorbital wrinkles)
Bunny lines (nasal bridge wrinkles)
Chin dimpling and lip lines
Masseter muscle reduction (jaw slimming)
Platysmal bands (neck rejuvenation)
Therapeutic (off-label) Uses:
Hyperhidrosis (underarms, palms, soles)
TMJ dysfunction and bruxism
Chronic migraine
Muscle spasticity and localized twitching
6. Example Dosage Guidelines
| Area | Units (U) |
|---|---|
| Glabella | 10–20 |
| Forehead | 8–15 |
| Crow’s feet (per side) | 6–12 |
| Masseter (per side) | 25–40 |
| Axillary hyperhidrosis | 50 per axilla |
Note: Final dosing should be based on patient anatomy and physician assessment.
7. Storage & Handling
Store at 2–8°C in the refrigerator; do not freeze
Reconstitute with 2.0–2.5 mL saline (4–5 U per 0.1 mL)
Gently roll to mix; do not shake vigorously
Use within the manufacturer-recommended period after dilution
Administered only by licensed and trained healthcare professionals
8. Safety & Contraindications
Avoid use in:
Patients with neuromuscular disorders (e.g., myasthenia gravis)
Pregnant or breastfeeding individuals
Active skin infections at the injection site
Known allergy to botulinum toxin ingredients
Monitor for typical mild side effects like localized swelling, bruising, or temporary eyelid droop, which are generally self-resolving.