One Tox 100 – Korean Botulinum Toxin Type A for Safe and Effective Aesthetic & Therapeutic Use
1. Overview & Manufacturer
One Tox 100 is a botulinum toxin type A product developed and manufactured in South Korea, designed for non-surgical facial aesthetics and emerging therapeutic indications. Although a newer name on the global market, One Tox is produced under GMP-compliant pharmaceutical standards and offers a cost-effective, high-purity neurotoxin option for clinics and medical professionals.2. Composition & Packaging
Each vial contains 100 units of Clostridium botulinum toxin type A, in lyophilized (freeze-dried) powder form
Requires reconstitution with 0.9% sterile saline (NaCl) prior to injection
Designed with low protein content, minimizing the risk of antibody development and ensuring long-term treatment success
Developed using modern purification and manufacturing techniques to ensure potency and safety
3. Mechanism of Action
One Tox works by inhibiting the release of acetylcholine at the neuromuscular junction. This temporary blockage results in:
Relaxation of overactive or expressive facial muscles
Reduction of dynamic wrinkles
Control of muscle-related conditions and excessive sweating (hyperhidrosis)
4. Key Advantages
Fast onset of action: Visible results typically begin within 2–4 days
Long-lasting effect: Effects generally last 3–6 months, depending on the area and dose
Smooth, controlled diffusion: Helps achieve natural-looking, symmetrical outcomes
High purity formulation: Reduces immunogenicity and supports repeat usage
Cost-effective: An excellent alternative to premium brands, especially for high-volume clinics
5. Clinical Applications
Aesthetic Treatments:
Glabellar lines (frown lines)
Forehead wrinkles
Crow’s feet
Bunny lines (nasal wrinkles)
Chin dimpling and lip lines
Masseter muscle reduction (jaw slimming)
Platysmal bands (neck lift)
Therapeutic (Off-label) Uses:
Hyperhidrosis (underarms, palms, soles)
Bruxism and TMJ tension
Facial muscle twitching or spasticity
Migraine prevention (emerging use)
6. Suggested Dosage Guidelines (Approximate ranges)
| Area | Units (U) |
|---|---|
| Glabella | 10–20 |
| Forehead | 8–15 |
| Crow’s feet (per side) | 6–12 |
| Masseter (per side) | 25–40 |
| Axillary sweating | 50 per axilla |
Dosing should be adjusted based on patient anatomy and treatment goals.
7. Storage & Handling
Store at 2–8°C (refrigerated); do not freeze
Protect from light and use reconstituted solution within the timeframe recommended by the manufacturer
Reconstitute gently with 2.0–2.5 mL saline (yielding 4–5 units per 0.1 mL)
Administer only by licensed healthcare professionals
8. Safety & Contraindications
Avoid in:
Pregnant or breastfeeding patients
Patients with known allergies to botulinum toxin
Individuals with neuromuscular disorders (e.g., myasthenia gravis)
Areas with active infection or skin inflammation
Common side effects may include mild bruising, swelling, or temporary eyelid droop. These are usually self-limiting and resolve without intervention.